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Sample Datasets for Perfusion MRI

This page provides links to publicly available contrast-agent based perfusion MRI datasets that can be used for research, development, and validation of analysis methods.

Overview

Sample datasets are essential resources for: - Developing and validating new analysis methods - Benchmarking different software tools - Reproducing published results - Training and education - Harmonizing acquisition and analysis protocols across sites

Available Datasets

QIN Breast DCE-MRI Dataset

Provider: Cancer Imaging Archive (TCIA), Quantitative Imaging Network (QIN)
Access: TCIA QIN Breast DCE-MRI
Description: Multisite, multivendor breast DCE-MRI data with associated clinical data. Includes pre-treatment and early-treatment images for monitoring response to neoadjuvant chemotherapy.

RIDER Neuro MRI Dataset

Provider: Cancer Imaging Archive (TCIA)
Access: TCIA RIDER Neuro MRI
Description: DCE-MRI and DSC-MRI scans of brain tumors with test-retest data for reproducibility assessment.

SPIE-AAPM-NCI PROSTATEx Challenge

Provider: Cancer Imaging Archive (TCIA)
Access: PROSTATEx
Description: Multiparametric MRI of the prostate including DCE-MRI sequences. Includes expert annotations for lesion classification.

Perfusion Training Dataset

Provider: OSIPI Task Force 4.1
Access: OSIPI Perfusion Training Dataset
Description: Standardized DCE-MRI and DSC-MRI datasets with known ground truth values, specifically curated for training and educational purposes.

DCE MRI Phantom Dataset

Provider: National Institute of Standards and Technology (NIST)
Access: NIST Quantitative MRI
Description: Phantom data for testing and validating DCE-MRI quantification methods with controlled conditions and known T1 values.

KISSDB (Kantonsspital St. Gallen Brain Dataset)

Provider: Kantonsspital St. Gallen, Switzerland
Access: KISSDB Website
Description: DSC-MRI brain perfusion dataset with manual segmentation of stroke lesions and tissue types.

Dataset Specifications

Dataset Modality Anatomy # of Subjects Field Strength Temporal Resolution AIF Available
QIN Breast DCE-MRI Breast 67 1.5T, 3T Variable Yes (some)
RIDER Neuro DCE/DSC Brain 19 1.5T, 3T 5-6s Yes
PROSTATEx DCE-MRI Prostate 204 3T 3.5-5s No
OSIPI Training DCE/DSC Various 20 1.5T, 3T Variable Yes
NIST Phantom DCE-MRI Phantom N/A 1.5T, 3T Variable N/A
KISSDB DSC-MRI Brain 151 1.5T 1-2s Yes

How to Use These Datasets

  1. Registration: Most datasets require user registration and agreement to data use terms
  2. Download: Follow the provider's instructions for downloading the data
  3. Format conversion: You may need to convert data to formats compatible with your analysis tools
  4. Documentation: Review the accompanying documentation for acquisition parameters and other metadata
  5. Citation: Always cite the dataset in your publications according to the provider's guidelines

Contributing

If you have a publicly available perfusion MRI dataset that you would like to add to this list, please see our contribution guidelines.

References

  1. Kalpathy-Cramer J, et al. Quantitative Imaging Network: Data Sharing and Competitive Algorithm Validation Leveraging The Cancer Imaging Archive. Transl Oncol. 2014;7(1):147-52.
  2. Shukla-Dave A, et al. Quantitative Imaging Biomarkers Alliance (QIBA) recommendations for improved precision of DWI and DCE-MRI derived biomarkers in multicenter oncology trials. J Magn Reson Imaging. 2019;49(7):e101-e121.
  3. Huang W, et al. Variations of dynamic contrast-enhanced magnetic resonance imaging in evaluation of breast cancer therapy response: a multicenter data analysis challenge. Transl Oncol. 2014;7(1):153-66.